Oxidative Stress and Aging

Definition

Disbalance between free radical production and the body's ability to neutralize them, which worsens with age. This oxidative stress damages proteins, lipids, and DNA, accelerating aging.

How it works

Free radicals are unstable molecules produced naturally by cellular metabolism, particularly by mitochondria. The body has natural antioxidant systems (superoxide dismutase, catalase, glutathione) to neutralize them. However, with age, free radical production increases, while antioxidant capacity declines. This oxidative stress damage DNA, creates mutations, and accelerates all aging processes. Environmental factors (pollution, UV, alcohol) increase oxidative stress further.

Role

Oxidative stress is a major cause of aging that damages all cellular structures and promotes chronic diseases.

Examples

• Antioxidant vitamins: C and E, beta-carotene
• Antioxidant minerals: zinc, selenium, copper
• Polyphenols: quercetin (garlic), anthocyanins (blueberries), catechins (green tea)

Recommendations

Consume daily antioxidant-rich foods (berries, carrots, red bell peppers, spinach). Prioritize selenium sources (Brazil nuts, fish) and vitamin E sources (almonds, avocados). Avoid tobacco, limit alcohol, and protect yourself from excessive sun exposure.

Key takeaway

Combating oxidative stress through antioxidant-rich nutrition is fundamental to preserve cell youthfulness.

Related terms