Water linked and structurally integrated into the body's macromolecules.
Water chemically integrated into organic molecules (proteins, lipids, carbohydrates) and not available for immediate osmotic reactions.
Bound or constitutional water represents approximately 1% of the total body water. It is chemically bonded to proteins, polysaccharides, and other macromolecules, forming a hydration layer around these structures. This water cannot freely cross cell membranes and does not participate in osmotic reactions. It plays a role in maintaining the structural stability of macromolecules and their three-dimensional conformation. Its importance increases in fibrous tissues such as collagen.
Maintains the structure and stability of biological macromolecules.
Understand that this water does not compensate for dehydration and that the intake of free water remains essential. Do not confuse with free water available for metabolic needs.
Bound water is structurally essential but does not contribute to physiological hydration.
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