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Allergies et intolérances alimentaires

EpiPen

Portable auto-injector of epinephrine for emergency treatment of anaphylaxis.

Definition

A portable auto-injector of epinephrine (adrenaline) used to rapidly treat anaphylaxis. It is a portable medical device designed for individuals suffering from severe and potentially life-threatening allergies.

How it works

EpiPen is a pen-style auto-injector containing epinephrine (adrenaline), the hormone that counters the effects of anaphylaxis in seconds. It works by rapidly releasing the hormone into the bloodstream, constricting blood vessels to restore blood pressure, relaxing airway smooth muscles to improve breathing, and suppressing mast cell degranulation. EpiPen devices are typically supplied in pairs, allowing for a second injection if necessary 5-15 minutes after the first. Even after a successful injection, urgent medical consultation remains mandatory.

Role

Emergency treatment that saves lives by blocking systemic effects of anaphylaxis and stabilizing the patient's condition.

Examples

  • EpiPen 0.3 mg for adults
  • EpiPen Jr 0.15 mg for children
  • Generic epinephrine auto-injectors
  • Jext
  • Emerade

Recommendations

Regularly check the expiration date of your EpiPen and replace it before expiration. Familiarize yourself with its use and train family members and caregivers on how to use it. Keep it nearby at all times, even at school or work.

Key takeaway

EpiPen is a vital device for individuals at risk of anaphylaxis and must be used immediately in case of severe reaction.

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