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Phytochimie et composés bioactifs

Glucosinolate

Sulfur molecules in cruciferous vegetables that convert to potent anticancer compounds during chewing.

Definition

Organosulfur glycosidic compounds that are precursors of isothiocyanates, abundant in cruciferous vegetables and released upon cellular rupture.

How it works

Glucosinolates are natural sulfur compounds stored in the cells of cruciferous vegetables such as broccoli, cabbage, and cauliflower. When these cells are damaged through chewing or cooking, an enzyme called myrosinase converts the glucosinolates into active isothiocyanates. These derived compounds possess strong anticancer, antioxidant, and anti-inflammatory properties. Regular consumption is associated with a reduced risk of several cancers.

Role

Precursor to anticancer and detoxifying compounds supporting cellular defense mechanisms.

Examples

  • Raw broccoli
  • Cauliflower
  • Kale
  • Raddish
  • Black radish

Recommendations

Eat cruciferous vegetables raw or lightly cooked to preserve enzymatic activity and conversion to isothiocyanates. Chew your cruciferous foods well to maximize release of active compounds. Vary types of cruciferous vegetables to benefit from a diverse range of glucosinolates.

Key takeaway

Glucosinolates in raw cruciferous vegetables offer optimal anticancer protection when converted into isothiocyanates through chewing.

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