Transferrin

Definition

A plasma protein synthesized by the liver, responsible for transporting iron in the blood to tissues and the bone marrow. It binds to iron, making it bioavailable for the body.

How it works

Transferrin is an important glycoprotein that ensures the safe transport of iron from intestinal absorption sites to cells that need it. It possesses two iron-binding sites, and saturation indicates body iron availability. Abnormal transferrin levels may indicate iron deficiency or excess, as well as hepatic or nutritional issues.

Role

Transports iron from plasma to cells for energy metabolism and hemoglobin synthesis.

Examples

• Evaluating anemia
• Diagnosing hemochromatosis
• Monitoring iron status
• Nutritional assessment

Recommendations

Regular transferrin dosage is recommended in suspected anemia or iron metabolism disorder. Combine with serum iron and ferritin for complete evaluation of iron status.

Key takeaway

Transferrin reflects iron transport capacity and aids in differentiating anemia types

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