Insulin Resistance and PCOS

Definition

Insulin resistance is a metabolic condition where cells respond poorly to insulin, often associated with PCOS. It promotes fat accumulation, hyperandrogenism, and disrupts ovulation.

How it works

Insulin resistance is a key factor in 70% of women with PCOS. In response, the pancreas produces more insulin (hyperinsulinemia), which stimulates the ovaries to produce more androgens. Excess male hormones prevent ovary maturation and promote anovulatory cycles. Insulin resistance also accelerates weight gain, creating a vicious cycle.

Role

Disrupts metabolism, increases androgens, and compromises ovulation in women with PCOS.

Examples

• Unexplained weight gain
• Sugar cravings
• Post-meal fatigue
• Acanthosis nigricans (skin darkening)
• Difficulty conceiving

Recommendations

Eliminate quick sugars and high-glycemic foods. Increase soluble fiber consumption (oats, lentils, apples) and practice regular exercise. A blood test can confirm insulin resistance and guide treatment.

Key takeaway

Mastering insulin resistance through nutrition is essential to improve PCOS fertility.

Related terms