Mobilization of fat reserves to produce energy.
Lipolysis is the process of breaking down triglycerides in adipose tissue into free fatty acids and glycerol, which are released into the blood to be used as an energy source.
Lipolysis is activated by catecholamines (adrenaline, noradrenaline), glucagon, and hormone-sensitive lipase during fasting or exercise. It is inhibited by insulin. The released fatty acids fuel mitochondrial beta-oxidation. Moderate-intensity exercise (50-65% VO2max) maximizes lipolysis.
Mobilize lipid reserves to provide energy between meals and during effort.
Regular moderate-intensity exercise and prolonged nighttime fasting optimize lipolysis.
Lipolysis is only truly activated when insulin is low — eating less frequently helps burn fat.
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