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Digestion & Absorption

Bile

Hepatic digestive fluid allowing fat absorption.

Definition

Bile is a hepatic secretion stored in the gallbladder and discharged into the duodenum during meals. It emulsifies lipids to make them accessible to pancreatic lipases.

How it works

Bile contains bile salts (cholesterol derivatives), bilirubin, cholesterol, and phospholipids. Bile salts emulsify lipids into micelles, increasing the contact surface for lipases. After fat absorption, they are reabsorbed in the ileum and recycled (enterohepatic cycle). Soluble fibers capture bile salts and reduce cholesterol.

Role

Emulsification of dietary lipids to enable digestion and absorption.

Examples

  • Inflamed gallbladder (cholecystitis)
  • Gallstones
  • Jaundice (bile in the blood)

Recommendations

Soluble fibers (oats, apple) reduce LDL-cholesterol by capturing bile salts.

Key takeaway

Soluble fibers lower cholesterol by intercepting bile salts before their recycling.

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